The Mouse Model of Down Syndrome Ts65Dn Presents Visual Deficits as Assessed by Pattern Visual Evoked Potentials

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The mouse model of Down syndrome Ts65Dn presents visual deficits as assessed by pattern visual evoked potentials.

PURPOSE The Ts65Dn mouse is the most complete widely available animal model of Down syndrome (DS). Quantitative information was generated about visual function in the Ts65Dn mouse by investigating their visual capabilities by means of electroretinography (ERG) and patterned visual evoked potentials (pVEPs). METHODS pVEPs were recorded directly from specific regions of the binocular visual cor...

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ژورنال

عنوان ژورنال: Investigative Opthalmology & Visual Science

سال: 2010

ISSN: 1552-5783

DOI: 10.1167/iovs.09-4465